The term bioavailability defines how much and how fast the nutrient or active ingredient gets to the site of action, thus affecting a person’s health and nutritional status. It applies to the bioactive food compounds and the oral medications as well. The bioavailability process mainly has the following stages some stages are liberation, absorption, distribution, metabolism, and elimination (LADME). [1]
Bioactive compounds from plant and animal sources are activities that will benefit if they are bioavailable. Learning how the ingestion of these compounds could improve health, and performance would be advantageous for health promotion.
The bioavailability of the nutrients depends not only on their concentration within a food product but also on their delivery of micronutrients to the human body for absorption and metabolism; in addition, other factors such as matrix effects, methods of preparation, or the presence of other compounds may also affect bioavailability. [2]
Advanced techniques applied at the food research lab (FRL) are complemented by the nutrient bioavailability value, which ensures that the diets maximally optimally avail health benefits for consumers.
The bioavailability of nutrients is distinct for acids from each other and has many influencing factors; for example, the chemical nature of the nutrient, the matrix in which the nutrient is contained in the food, or the presence of other constituents known to enhance or inhibit the absorption of nutrients. Besides those factors, personal determinants for health, genotypes, age, and lifestyle greatly improve the absorption and utilization of nutrients within the body system. [3]
Optimizing nutrient bioavailability is an essential element in the promotion of health and wellness. For instance, some vitamins and minerals can only be absorbed optimally when taken together with some fats or proteins, while some are prevented from being absorbed by phytates, tannins, or dietary fiber.
Understanding these factors is vital in improving the nutritional quality of food products. Thus, it can become an important tool in formulating strategies to increase the absorption capacity of nutrients and the overall health benefit. [4]
1. Optimizing Food Matrix At FRL, researchers are attempting to optimize the food matrix-that is, modify the physical and chemical structure of food for the release and absorption of nutrients. This may include, but will not be limited to, modifying the size of food particles, and emulsifying, or encapsulating nutrients within the protective carrier materials to prevent the degradation of nutrients during digestion. Designed food matrices ensure that nutrients will be available for better absorption within the gastrointestinal tract from different perspectives at FRL. [5]
2. BiofortificationBiofortification is the process of improving nutritional value using agricultural practice, conventional way of plant breeding, or modern biotechnological intervention to raise essential nutrients, vitamins, and minerals in staple crops. At FRL, together with agriculturalists, they work on improving the levels of nutrients, vitamins, and minerals in staple foods. By developing biofortified crops, FRL is targeting nutrient deficiencies in populations that rely on these foods as dietary staples for the improved health status of these populations. [6]
3. FermentationAn ancient technique for food preservation, fermentation also enriches the nutritional quality of foods. FRL exploits fermentation systems therefore boosting the bioavailability of nutrients, especially minerals and vitamins. During fermentation, probiotic microorganisms degrade complex substrates and hence render nutrients more available. For instance, in cereal grains, lactic acid bacteria can assist in increasing the bioavailability of iron and zinc in poorly absorbed forms due to the presence of phytates. [7]
4. Nanoencapsulation: Nanoencapsulation is used in FRL to stabilize nutrient delivery and enhance the effect of these nutrients. The use of nano-sized carriers encapsulates nutrients, thus improving their solubility, stability, and bioavailability. Such a technique is especially useful for sensitive nutrients such as omega-3 fatty acids, which tend to undergo oxidation. Nanoencapsulation buffers nutrients until they reach the target site in the body, thereby enhancing their absorption rate. [8]
5. Use of Enzymes: Enzymes are the basis for the enzymatic treatments undertaken at FRL. Most commonly, they are used to enhance the nutrient bioavailability by hydrolysis of complex food matrices. These enzymes are utilized to hydrolyze protein, fat, and carbohydrate to generate smaller, more bioavailable nutrients. For example, a protease for the expansion of amino acid relative availability, being absorbed through carbohydrates, enhances carbohydrate absorption. Such an approach maximally optimizes nutrients in food products. [2]
6. Formulation with Nutrient Enhancers: The work of FRL researchers focuses on formulating food products by developing natural nutrient enhancers to improve absorption. For instance, the role of vitamin C is increased in iron absorption from plant sources, while fat increases the bioavailability of -soluble vitamins (A, D, E, and K). The nutrient value of foodstuffs is enhanced by the respective combinations of ingredients so that such food products are made available to the ultimate consumer. [9]
7. Functional Food Development: Functional foods consisting of beneficial bioactive compounds such as prebiotics, probiotics, etc., are a significant aspect of FRL developing functional foods. Health benefits beyond basic nutrition will be given to people through bioactivity by these products. Many functional foods are made by FRL, which are enhanced by the above ingredients for gut health and nutrient absorption. For example, including prebiotics may encourage beneficial gut bacteria that may improve overall nutrient absorption and utilization. [10]
8. Personalized Nutrition Approaches Variation in digestion and metabolism leads to variations in the bioavailability of nutrients. Keeping in view this aspect, research is being conducted for personalized nutrition that includes the genetic, metabolic, and microbiome profiles of individuals. This affords prescribing suitable dietary recommendations and products optimized for nutrient absorption and health outcomes for the diversity in the population.
9. Research and Collaboration: It conducts ongoing research and collaboration with academic institutions, industry partners, and healthcare professional organizations to improve the science of nutrient bioavailability. FRL continues to put its advanced techniques and products through tests and trials on-site via clinical studies and trials. This approach is intended to stimulate innovation and guarantee that the methods of use are scientific. [11]
These advances to improving nutrient bioavailability at FRL prove very human-friendly. Nutrient bioavailability through FRL implies the treatment of nutrient-associated diseases such as malnutrition, micronutrient deficiency, or diet-related diseases. Working on functional foods and biofortified crops is thus contributing to foods promoting greater health for the vulnerable sector. [12]
In addition, a vital aspect of FRL’s mission is to educate the public about the importance of nutrient bioavailability and how to maximize this from their foods. They impart to society all relevant information, knowledge, and resources that would help empower the choice of foods supporting the healthy existence of the communities.
It is therefore important to improve bioavailability to realize the health benefits and effectiveness of food products. In this context, the Food Research Lab deploys several modern applications such as optimization of food matrix systems, fermentation, nanoencapsulation, and personalized nutrition approaches to help improve nutrient absorption and bioavailability. By strategically addressing the hurdle of nutrient bioavailability, FRL acts as a pioneer in offering innovative solutions for public health, enabling people to achieve optimum nutrition and well-being. FRL will pursue an ever-deepening commitment to nutrition as research progresses to ensure that people enjoy food that maintains health while delivering nutrition.
Food Research Lab strives for excellence in new Food, Beverage and Nutraceutical Product Research and Development by offering cutting edge scientific analysis and expertise.